About gender: there is a lot between male and female (not only XXY and other genetic variations on the X/Y things but other genetics are important to for your gender and sex (or other words with about the same meaning).
It's an important point that actually lots of people don't fit the male and female categories that supposedly exist in biology. There are various combinations of chromosomes. The idea that the species is divided into two groups; males and females, is a political fabrication.
Sex and gender were categories invented by one powerful group in order to control the other. People with penises invented the categories man and women in order to control, dominate and exploit those without penises, as well as each other.
Still today thousands of years later babies are assigned a gender at birth based on the same criteria in the interests of reproducing male supremacy.
When people express and determine their identities autonomous of (and in opposition to) the logic of male supremacy it is a resistance to the logic that says people with penises should control, dominate and exploit those without. As such, anyone who isn't a bellend should stand in solidarity alongside queer and trans folk. Most men won't because it challenges their power as men - they will attack and de-legitimise because it is by preserving the categories 'man' and 'woman' (as determined by genitals) that they preserve the basis of their privilege.
I'm a male geek, I'm nothing like a male sports fan. I have more in common with female geeks.
"You - who I oppress and exploit and benefit at the expense of - I am just like you." Arrogant sod.